Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761051 | 1.00 | ALDH1A1 (0.38) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA | |
| SCHEMBL21338487 | 0.93 | ALDH1A1 (0.37) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA | |
| SCHEMBL12205327 | 0.93 | ALDH1A1 (0.37) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA | |
| SCHEMBL12206758 | 0.93 | ALDH1A1 (0.37) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA | |
| SCHEMBL8506443 | 0.92 | NPSR1 (0.40) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA | |
| SCHEMBL2412684 | 0.91 | ALDH1A1 (0.41) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA | |
| SCHEMBL29501170 | 0.91 | ALDH1A1 (0.41) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA | |
| SCHEMBL2599669 | 0.90 | KDM4E (0.39) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA | |
| SCHEMBL14092910 | 0.89 | SMN1; SMN2 (0.33) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA | |
| SCHEMBL675528 | 0.89 | MAPT (0.36) | ALDH1A1NPSR1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559713-A1 | Chromene compound | Tokuyama Corporation (JP) | 2005-08-03 | — | — | EP | disclosed |
| EP-1122251-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-6525194-B1 | Naphtho-2,1-b-pyran derivative that develops yellow to red color | TOKUYAMA CORPORATION (JP) | 2003-02-25 | — | — | US | disclosed |
| US-20030028019-A1 | Chromene compound | MOMODA JUNJI (JP) | 2003-02-06 | — | — | US | disclosed |
| EP-1122251-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 2001-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028019-A1 | Chromene compound | MITF, TYR, CDYL | ALDH1A1 4063/4885NPSR1 4153/4885KDM4E 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.