Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.64 |
| ▸ | CES1 | P23141 | 2/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.50 |
| ▸ | FEN1 | P39748 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylpyruvate SCHEMBL468389 | 0.91 | CES1 (0.76) | CES2CES1AKR1B1FNTAFNTB | |
| Phenylpyruvate SCHEMBL11297524 | 0.89 | CES1 (0.73) | CES2CES1AKR1B1FNTAFNTB | |
| Phenylpyruvate SCHEMBL28203540 | 0.89 | CES1 (0.80) | CES2CES1AKR1B1FNTAFNTB | |
| Phenylpyruvate SCHEMBL43235 | 0.89 | CES1 (0.80) | CES2CES1AKR1B1FNTAFNTB | |
| Phenylpyruvate SCHEMBL11193388 | 0.87 | CES1 (0.76) | CES2CES1AKR1B1FNTAFNTB | |
| Phenylpyruvate SCHEMBL9217988 | 0.87 | CES1 (0.76) | CES2CES1AKR1B1FNTAFNTB | |
| Phenylpyruvate SCHEMBL28233246 | 0.87 | CES1 (0.76) | CES2CES1AKR1B1FNTAFNTB | |
| Phenylpyruvate SCHEMBL28232350 | 0.87 | CES1 (0.76) | CES2CES1AKR1B1FNTAFNTB | |
| Phenylpyruvate SCHEMBL3408866 | 0.87 | CES1 (0.76) | CES2CES1AKR1B1FNTAFNTB | |
| Phenylpyruvate SCHEMBL27281240 | 0.87 | CES1 (0.76) | CES2CES1AKR1B1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697416-B2 | Recombinant polynucleotide, host cells containing the same and a process for producing a protein having aldolase activity | AJINOMOTO CO., INC. (JP) | 2014-04-15 | — | — | US | disclosed |
| CN-103525847-A | Novel aldolases and process for producing substituted alpha-keto acid | AJINOMOTO KK | 2014-01-22 | — | — | CN | disclosed |
| US-8563278-B2 | Process of producing glutamate derivatives | AJINOMOTO CO., INC. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20130252310-A1 | NOVEL ALDOLASE AND PRODUCTION PROCESS OF SUBSTITUTED ALPHA-KETO ACIDS | AJINOMOTO, CO., INC. (JP) | 2013-09-26 | — | — | US | disclosed |
| US-8535920-B2 | Such as monatin by exposing typtophan to enzyme which converts tryptophan to 3-indolepyruvic acid which is exposed to enzyme and oxaloacetic/pyruvic acid to form 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid | AJINOMOTO CO., INC. (JP) | 2013-09-17 | — | — | US | disclosed |
| CN-1678742-B | Novel aldolase and process for producing substituted alpha-keto acid | AJINOMOTO KK | 2013-07-17 | — | — | CN | disclosed |
| US-20130157342-A1 | NOVEL ALDOLASE AND PRODUCTION PROCESS OF SUBSTITUTED ALPHA-KETO ACIDS | AJINOMOTO CO., INC. (JP) | 2013-06-20 | — | — | US | disclosed |
| US-8273556-B2 | Aldolase and production process of substituted α-keto acids | AJINOMOTO CO., INC. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-8202711-B2 | Process for producing glutamate derivatives | AJINOMOTO CO., INC. (JP) | 2012-06-19 | — | — | US | disclosed |
| US-20120040416-A1 | NOVEL ALDOLASE AND PRODUCTION PROCESS OF SUBSTITUTED ALPHA-KETO ACIDS | AJINOMOTO CO., INC. (JP) | 2012-02-16 | — | — | US | disclosed |
| CN-101671707-A | Process for producing glutamate derivatives | AJINOMOTO KK | 2010-03-17 | — | — | CN | disclosed |
| CN-100549182-C | Process for preparing glutamic acid derivatives | AJINOMOTO KK (JP) | 2009-10-14 | — | — | CN | disclosed |
| US-20080318290-A1 | NOVEL ALDOLASE AND PRODUCTION PROCESS OF SUBSTITUTED ALPHA-KETO ACIDS | AJINOMOTO CO., INC. (JP) | 2008-12-25 | — | — | US | disclosed |
| US-20080199921-A1 | PROCESS FOR PRODUCING GLUTAMATE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2008-08-21 | — | — | US | disclosed |
| US-7297800-B2 | Process of producing glutamate derivatives | AJINOMOTO CO., INC. (JP) | 2007-11-20 | — | — | US | disclosed |
| US-20070072277-A1 | PROCESS FOR PRODUCING GLUTAMATE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2007-03-29 | — | — | US | disclosed |
| CN-1678742-A | Novel aldolase and process for producing substituted alpha-keto acid | AJINOMOTO KK (JP) | 2005-10-05 | — | — | CN | disclosed |
| CN-1610749-A | Process for preparing glutamic acid derivatives | AJINOMOTO KK (JP) | 2005-04-27 | — | — | CN | disclosed |
| EP-0954596-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES | PHYTON, INC. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1997044476-A1 | ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES | PHYTON, INC. (US) | 1997-11-27 | — | — | WO | disclosed |