Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172194 | 0.91 | MEN1 (0.53) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL6170426 | 0.90 | KMT2A (0.71) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL6170246 | 0.87 | KMT2A (0.50) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL6170924 | 0.85 | MEN1 (0.54) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL6171096 | 0.83 | MEN1 (0.46) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL6171548 | 0.83 | KMT2A (0.47) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL6172271 | 0.78 | RAB9A (0.51) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL31353162 | 0.77 | MAOB (0.49) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL13927436 | 0.74 | ALDH1A1 (0.54) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL31353380 | 0.74 | PRKAB2 (0.46) | RAB9ANPC1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097138-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LAFON LABOR (FR) | 2005-12-07 | — | — | EP | claimed |
| US-6593342-B1 | Activity on the proliferation of clonogenic cells in tumours and comprising an efficient amount of a compound selected among the compounds | LABORATOIRE L. LAFON (FR) | 2003-07-15 | — | — | US | claimed |
| WO-2002022074-A2 | USE OF 2- AND 4- QUINOLONES FOR INHIBITING INTIMAL NEO-PROLIFERATION | LABORATOIRE L. LAFON (FR) | 2002-03-21 | — | — | WO | claimed |
| EP-1097138-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2001-05-09 | — | — | EP | claimed |
| WO-2000003990-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | claimed |
| EP-1097138-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LAFON LABOR (FR) | 2005-12-07 | — | — | EP | disclosed |
| US-6593342-B1 | Activity on the proliferation of clonogenic cells in tumours and comprising an efficient amount of a compound selected among the compounds | LABORATOIRE L. LAFON (FR) | 2003-07-15 | — | — | US | disclosed |
| WO-2002022074-A2 | USE OF 2- AND 4- QUINOLONES FOR INHIBITING INTIMAL NEO-PROLIFERATION | LABORATOIRE L. LAFON (FR) | 2002-03-21 | — | — | WO | disclosed |
| EP-1097138-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003990-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |