Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | PPARA | Q07869 | 4/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | EGFR | P00533 | 5/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214773 | 0.88 | LTA4H (0.61) | MAOBPPARAPPARGEGFRALOX5 | |
| SCHEMBL28441594 | 0.85 | PPARA (0.62) | MAOBPPARAPPARGALOX5PPARD | |
| SCHEMBL8000823 | 0.83 | PPARG (0.63) | MAOBPPARAPPARGPPARDFFAR1 | |
| SCHEMBL6716294 | 0.82 | PPARA (0.60) | MAOBPPARAPPARGALOX5PPARD | |
| SCHEMBL5966473 | 0.81 | PPARG (0.58) | MAOBPPARAPPARGPPARDFFAR1 | |
| SCHEMBL6483824 | 0.81 | MAOB (0.62) | MAOBPPARAPPARGALOX5PPARD | |
| SCHEMBL28860722 | 0.81 | FFAR1 (0.64) | PPARAPPARGPPARDFFAR1FFAR4 | |
| SCHEMBL28224291 | 0.81 | FFAR1 (0.64) | PPARAPPARGPPARDFFAR1FFAR4 | |
| SCHEMBL11433596 | 0.80 | MAOB (0.58) | MAOBPPARAPPARGALOX5PTGS1 | |
| SCHEMBL7632753 | 0.80 | PPARG (0.61) | MAOBPPARAPPARGALOX5PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888341-B1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | AVENTIS PHARMA SA (FR) | 2005-11-30 | — | — | EP | disclosed |
| EP-0888341-A1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032874-A1 | NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES | HOECHST MARION ROUSSEL (FR) | 1997-09-12 | — | — | WO | disclosed |