Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228556 | 0.80 | KMT2A (0.62) | NR1H4SMN1; SMN2TP53THRBPPARG | |
| SCHEMBL5227493 | 0.77 | KMT2A (0.58) | NR1H4SMN1; SMN2TP53PPARGPPARA | |
| SCHEMBL6170952 | 0.76 | NPC1 (0.56) | NR1H4SMN1; SMN2PPARGPPARAMAPT | |
| SCHEMBL6170875 | 0.75 | NR1H4 (0.46) | NR1H4SMN1; SMN2TP53THRBPPARG | |
| SCHEMBL7371977 | 0.73 | NR1H4 (0.46) | NR1H4SMN1; SMN2TP53THRBPPARG | |
| SCHEMBL8768802 | 0.72 | NPSR1 (0.58) | NR1H4KMT2AMAPTNPSR1LMNA | |
| SCHEMBL6169267 | 0.72 | TP53 (0.43) | NR1H4SMN1; SMN2TP53THRBPPARG | |
| SCHEMBL6809277 | 0.71 | SLC6A3 (0.72) | SMN1; SMN2KMT2AMAPTNPSR1LMNA | |
| SCHEMBL7328743 | 0.69 | MAPT (0.66) | NR1H4SMN1; SMN2TP53PPARGPPARA | |
| SCHEMBL5315452 | 0.68 | RAB9A (0.70) | NR1H4SMN1; SMN2TP53PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2005-06-08 | — | — | EP | disclosed |