Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18317487 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2MAOAKMT2AMEN1KDM4E | |
| SCHEMBL10757723 | 0.78 | DAO (0.59) | SMN1; SMN2KMT2AMEN1KDM4EMAPT | |
| SCHEMBL1054636 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2AMEN1KDM4ENPC1 | |
| SCHEMBL11747741 | 0.76 | KMT2A (0.59) | SMN1; SMN2MAOAKMT2AMEN1RAB9A | |
| SCHEMBL9499552 | 0.75 | DAO (0.51) | KMT2ARAB9AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL18523561 | 0.74 | HTR4 (0.43) | KMT2ARAB9AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL11766114 | 0.73 | ALDH1A1 (0.51) | SMN1; SMN2KMT2ARAB9AKDM4EHSD17B10 | |
| SCHEMBL2185903 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2MAOAKMT2AMEN1KDM4E | |
| SCHEMBL11178545 | 0.71 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AKDM4EALDH1A1LYN | |
| SCHEMBL18536962 | 0.71 | LYN (0.56) | SMN1; SMN2KMT2AMEN1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097138-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-QUINOLONES | LAFON LABOR (FR) | 2005-12-07 | — | — | EP | disclosed |