Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172823 | 0.86 | RAB9A (0.47) | OXTRMAPTLMNANPSR1RAB9A | |
| SCHEMBL6172817 | 0.82 | MAPT (0.43) | MAPTKMT2ALMNANPSR1RAB9A | |
| SCHEMBL6097690 | 0.74 | MEN1 (0.53) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL6096779 | 0.70 | NPC1 (0.40) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL4089380 | 0.69 | ALDH1A1 (0.61) | MAPTMEN1KMT2ANPSR1RAB9A | |
| SCHEMBL6096848 | 0.66 | KDM4E (0.42) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL3683672 | 0.65 | ALDH1A1 (0.50) | MAPTNPSR1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6100494 | 0.65 | CHRNB2 (0.43) | MAPTMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL9267264 | 0.64 | ALDH1A1 (0.56) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL13341592 | 0.63 | KMT2A (0.41) | MAPTMEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495005-A1 | PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | Pfizer Japan Inc. (JP) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087061-A1 | PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER JAPAN INC. (JP) | 2003-10-23 | — | — | WO | disclosed |