SCHEMBL617270

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1167966	0.82	KMT2A (0.65)	KMT2AMAPTMEN1LMNAALDH1A1
	SCHEMBL615374	0.81	KMT2A (0.63)	KMT2AMAPTMEN1LMNAALDH1A1
	SCHEMBL1167631	0.79	KMT2A (0.63)	KMT2AMAPTMEN1LMNAALDH1A1
	SCHEMBL617788	0.77	KIT (0.47)	KMT2AMAPTLMNAALDH1A1HTT
	SCHEMBL412113	0.76	MAPT (0.64)	KMT2AMAPTMEN1LMNAALDH1A1
	SCHEMBL618904	0.76	PTGS2 (0.44)	MAPTLMNAALDH1A1TDP1HTT
	SCHEMBL30203856	0.74	KMT2A (0.67)	KMT2AMAPTMEN1LMNAALDH1A1
	SCHEMBL22672258	0.74	KMT2A (0.67)	KMT2AMAPTMEN1LMNAALDH1A1
	SCHEMBL16471461	0.74	GABRA1 (0.46)	KMT2AMAPTMEN1LMNAALDH1A1
	SCHEMBL616208	0.74	MEN1 (0.47)	KMT2AMAPTMEN1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.