Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | LIPE | Q05469 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175577 | 0.93 | EPHX2 (0.40) | EPHX2LIPELMNAHRH3KCNA5 | |
| SCHEMBL6251397 | 0.92 | EPHX2 (0.39) | EPHX2LIPELMNAKCNA5 | |
| SCHEMBL6175321 | 0.90 | KCNA5 (0.41) | LIPELMNAKCNA5 | |
| SCHEMBL6170501 | 0.87 | LMNA (0.42) | EPHX2LIPELMNACXCR3POLB | |
| SCHEMBL6173948 | 0.87 | IGF1R (0.33) | LMNAPOLBPDE2A | |
| SCHEMBL6176359 | 0.86 | LMNA (0.39) | LIPELMNACXCR3POLBL3MBTL1 | |
| SCHEMBL6174458 | 0.84 | SLC5A1 (0.40) | LIPELMNACXCR3POLBL3MBTL1 | |
| SCHEMBL6173353 | 0.83 | LMNA (0.45) | LIPELMNACXCR3POLBPDE2A | |
| SCHEMBL6171386 | 0.81 | LMNA (0.38) | LIPELMNACXCR3POLBL3MBTL1 | |
| SCHEMBL6173172 | 0.81 | LMNA (0.41) | LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |