SCHEMBL617346

SCHEMBL617346

COc1c(-c2ccccc2)cccc1C(C)C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.43
PDE4A P27815 3/20 0.43
PDE4C Q08493 3/20 0.43
PDE4D Q08499 3/20 0.43
MITF O75030 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
ALOX5AP P20292 1/20 0.40
FEN1 P39748 1/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
GABRA1 P14867 2/20 0.38
GABRG2 P18507 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27601380 0.85 ALOX5AP (0.43) PDE4BPDE4APDE4CPDE4DMITF
SCHEMBL1643869 0.85 LPAR1 (0.37) PDE4BPDE4APDE4CPDE4DMITF
SCHEMBL13385087 0.82 PDE4B (0.48) PDE4BPDE4APDE4CPDE4DMITF
SCHEMBL19068879 0.81 HDAC4 (0.42) PDE4BPDE4APDE4CPDE4DMITF
SCHEMBL1642703 0.80 PDE4B (0.51) PDE4BPDE4APDE4CPDE4DALDH1A1
SCHEMBL20150115 0.80 CYP17A1 (0.35) CA1CA2GABRA1GABRG2GABRB3
SCHEMBL5548772 0.80 GABRA1 (0.50) ALDH1A1CA1CA2GABRA1GABRG2
SCHEMBL1644446 0.78 G6PD (0.38) PDE4BPDE4APDE4CPDE4DALDH1A1
SCHEMBL1644449 0.78 G6PD (0.38) PDE4BPDE4APDE4CPDE4DALDH1A1
SCHEMBL146177 0.78 CA1 (0.58) ALDH1A1CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2324067-B1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SABIC SK NEXLENE COMPANY PTE LTD (SG) 2018-04-25 EP disclosed
EP-1910427-B1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK INNOVATION CO LTD (KR) 2015-05-13 EP disclosed
US-8674026-B2 Ethylene copolymer having multiple pitch in molecular weight distribution and the method of preparing the same SK INNOVATION CO., LTD. (KR) 2014-03-18 US disclosed
EP-2185611-B1 ETHYLENE COPOLYMER HAVING MULTIPLE PITCH IN MOLECULAR WEIGHT DISTRIBUTION AND THE METHOD OF PREPARING THE SAME SK INNOVATION CO LTD (KR) 2013-03-27 EP disclosed
US-20120141702-A1 ETHYLENE COPOLYMER HAVING MULTIPLE PITCH IN MOLECULAR WEIGHT DISTRIBUTION AND THE METHOD OF PREPARING THE SAME SK ENERGY CO., LTD. (KR) 2012-06-07 US disclosed
US-20120041149-A1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SK INNOVATION CO., LTD. (KR) 2012-02-16 US disclosed
US-8076428-B2 Ethylene copolymer having multiple pitch molecular weight distribution and the method of preparing the same SK ENERGY CO., LTD. (KR) 2011-12-13 US disclosed
US-8067511-B2 Ethylene copolymer and a method of preparing the same SK INNOVATION CO., LTD. (KR) 2011-11-29 US disclosed
EP-2324067-A2 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SK Energy Co., Ltd. (KR) 2011-05-25 EP disclosed
US-7833926-B2 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins SK ENERGY CO., LTD. (KR) 2010-11-16 US disclosed
EP-2185611-A2 ETHYLENE COPOLYMER HAVING MULTIPLE PITCH IN MOLECULAR WEIGHT DISTRIBUTION AND THE METHOD OF PREPARING THE SAME SK Energy Co., Ltd. (KR) 2010-05-19 EP disclosed
US-20100120981-A1 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SABIC SK NEXLENE COMPANY PTE. LTD. (SG) 2010-05-13 US disclosed
WO-2010030145-A2 ETHYLENE COPOLYMER AND A METHOD OF PREPARING THE SAME SK ENERGY CO., LTD. (KR) 2010-03-18 WO disclosed
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK ENERGY CO., LTD. (KR) 2009-12-31 US disclosed
US-7589042-B2 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and α-olefins SK CORPORATION (KR) 2009-09-15 US disclosed
WO-2009031798-A2 ETHYLENE COPOLYMER HAVING MULTIPLE PITCH IN MOLECULAR WEIGHT DISTRIBUTION AND THE METHOD OF PREPARING THE SAME SK ENERGY CO., LTD. (KR) 2009-03-12 WO disclosed
EP-1910427-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK Energy Co., Ltd. (KR) 2008-04-16 EP disclosed
US-20070135297-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK CORPORATION (KR) 2007-06-14 US disclosed
WO-2007040294-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-04-12 WO disclosed
US-20070004586-A1 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins SK CORPORATION (KR) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326175-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS ESR1, ERO1A, PPOX PDE4B 4701/4885PDE4A 4418/4885PDE4C 4841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.