Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175204 | 0.91 | IGF1R (0.38) | ALDH1A1TP53MDM2TACR1HTT | |
| SCHEMBL6175279 | 0.90 | FKBP1A (0.37) | ALDH1A1MEN1KMT2ATACR1IGF1R | |
| SCHEMBL6172665 | 0.87 | SLC6A9 (0.38) | ALDH1A1MEN1KMT2ATP53USP2 | |
| SCHEMBL6174315 | 0.85 | IGF1R (0.41) | ALDH1A1LMNAIGF1R | |
| SCHEMBL6171813 | 0.83 | IGF1R (0.41) | ALDH1A1LMNAIGF1R | |
| SCHEMBL6172569 | 0.83 | IGF1R (0.36) | ALDH1A1KMT2ALMNAIGF1R | |
| SCHEMBL6173461 | 0.81 | IGF1R (0.39) | ALDH1A1MEN1KMT2ATP53TACR1 | |
| SCHEMBL6172480 | 0.80 | IGF1R (0.39) | ALDH1A1LMNAIGF1R | |
| SCHEMBL6173832 | 0.79 | IGF1R (0.40) | ALDH1A1KMT2ATSHRLMNAIGF1R | |
| SCHEMBL6174310 | 0.78 | IGF1R (0.43) | ALDH1A1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |