Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176027 | 0.91 | HRH4 (0.33) | SLC6A9TP53MDM2ALDH1A1HTT | |
| SCHEMBL6175091 | 0.90 | SLC6A9 (0.34) | SLC6A9LMNAMAPK1ALDH1A1TSHR | |
| SCHEMBL6173489 | 0.90 | DPP4 (0.36) | SLC6A9LMNAMAPK1ALDH1A1TSHR | |
| SCHEMBL6173517 | 0.87 | ALDH1A1 (0.36) | LMNAMAPK1TP53MDM2MEN1 | |
| SCHEMBL6177902 | 0.83 | CYP2C9 (0.35) | LMNATP53MEN1ALDH1A1KMT2A | |
| SCHEMBL6172103 | 0.83 | RXFP1 (0.42) | LMNAL3MBTL1ALDH1A1HTT | |
| SCHEMBL6171994 | 0.83 | ALDH1A1 (0.37) | LMNAMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6173425 | 0.82 | LMNA (0.38) | SLC6A9LMNAMAPK1MAPTRECQL | |
| SCHEMBL6172898 | 0.82 | SLC6A9 (0.38) | SLC6A9LMNAMAPK1TP53MEN1 | |
| SCHEMBL6172896 | 0.82 | IGF1R (0.39) | SLC6A9LMNAMAPK1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |