SCHEMBL6173641

SCHEMBL6173641

C=C(C(=O)O)C(C=CC(=O)O)CCN

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.36
GABRD O14764 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB1 P18505 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36
GABRA2 P47869 2/20 0.36
GABRB2 P47870 2/20 0.36
GABRA4 P48169 2/20 0.36
GABRE P78334 2/20 0.36
GABRA6 Q16445 2/20 0.36
GABRG1 Q8N1C3 2/20 0.36
GABRG3 Q99928 2/20 0.36
GABRQ Q9UN88 2/20 0.36
GABRR1 P24046 4/20 0.34
GABRR2 P28476 2/20 0.34
BLM P54132 2/20 0.34
GABRR3 A8MPY1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11304196 0.81 GABRP (0.32) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8357531 0.79 ACHE (0.47) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2228649 0.79 GABRP (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11835021 0.77 LMNA (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL2312542 0.69 ALDH1A1 (0.30)
SCHEMBL357768 0.67 GABRP (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL6268226 0.67 GRIK1 (0.41) GABRR1BLMKMT2A
SCHEMBL696494 0.63
Methacrylic Acid SCHEMBL11062934 0.63 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2
Maleic Acid SCHEMBL18065037 0.62 TSHR (0.64) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0242761-B1 COMPOSITE MEMBRANES USEFUL IN THE SEPARATION OF LOW MOLECULAR WEIGHT ORGANIC COMPOUNDS FROM AQUEOUS SOLUTIONS CONTAINING INORGANIC SALTS ALIGENA AG (CH) 1990-08-29 EP claimed
US-4767645-A COATING MEMBRANE WITH HYDROPHILIC POLYMER AND CROSSLINKING ALIGENA AG (CH) 1988-08-30 US claimed
EP-0242761-A2 Composite membranes useful in the separation of low molecular weight organic compounds from aqueous solutions containing inorganic salts ALIGENA AG (CH) 1987-10-28 EP claimed
EP-0955327-B1 Poly-perfluoroalkyl substituted polyamines as grease proofing agents for paper and foam stabilizers in aqueous fire-fighting foams CIBA SC HOLDING AG (CH) 2005-05-18 EP disclosed
EP-1153061-B1 PERFLUOROALKYL-SUBSTITUTED AMINO ACID OLIGOMERS OR POLYMERS AND THEIR USE AS FOAM STABILIZERS IN AQUEOUS FIRE-FIGHTING-FOAM AGENTS AND AS OIL REPELLENT PAPER AND TEXTILE FINISHES CIBA SC HOLDING AG (CH) 2005-02-16 EP disclosed
US-6436306-B1 POLYAMINES USED IN NONPOLAR SOLVENT FIRE EXTINGUISHERS; SOLVENT RESISTANT, GREASEPROOF, AMPHOTERIC SURFACTANT CIBA SPECIALTY CHEMICALS CORPORATION 2002-08-20 US disclosed
US-6365676-B1 PERFLUOROALKYL IODIDE IN WATER WITH TERMINAL OLEFINS AND SOLVENTS CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-02 US disclosed
EP-1153061-A1 PERFLUOROALKYL-SUBSTITUTED AMINO ACID OLIGOMERS OR POLYMERS AND THEIR USE AS FOAM STABILIZERS IN AQUEOUS FIRE-FIGHTING-FOAM AGENTS AND AS OIL REPELLENT PAPER AND TEXTILE FINISHES Ciba SC Holding AG (CH) 2001-11-14 EP disclosed
US-6156222-A Poly-perfluoroalkyl substituted polyamines as grease proofing agents for paper and foam stabilizers in aqueous fire-fighting foams CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-12-05 US disclosed
WO-2000043438-A1 PERFLUOROALKYL-SUBSTITUTED AMINO ACID OLIGOMERS OR POLYMERS AND THEIR USE AS FOAM STABILIZERS IN AQUEOUS FIRE-FIGHTING-FOAM AGENTS AND AS OIL REPELLENT PAPER AND TEXTILE FINISHES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-07-27 WO disclosed
EP-0955327-A2 Poly-perfluoroalkyl substituted polyamines as grease proofing agents for paper and foam stabilizers in aqueous fire-fighting foams Ciba SC Holding AG (CH) 1999-11-10 EP disclosed
EP-0242761-B1 COMPOSITE MEMBRANES USEFUL IN THE SEPARATION OF LOW MOLECULAR WEIGHT ORGANIC COMPOUNDS FROM AQUEOUS SOLUTIONS CONTAINING INORGANIC SALTS ALIGENA AG (CH) 1990-08-29 EP disclosed
US-4889636-A HYDROPHILIC, CROSSLINKED POLYMERIC FILM CHEMICALLY BONDED TO POLYMERIC SUPPORT OPTIONALLY CROSSLINKED; DYNAMIC, BIFURCATED, SOLVENT AND COMPACTION RESISTANCE ALIGENA, AG 1989-12-26 US disclosed
US-4833014-A CROSSLINKED HYDROPHILIC POLYMER COATING ON SUPPORT ALIGENA AG (CH) 1989-05-23 US disclosed
US-4778596-A CROSSLINKED HYDROPHILIC POLYMER; FOR REVERSE OSMOSIS AND ULTRAFILTRATION ALIGENA AG (CH) 1988-10-18 US disclosed
US-4767645-A COATING MEMBRANE WITH HYDROPHILIC POLYMER AND CROSSLINKING ALIGENA AG (CH) 1988-08-30 US disclosed
US-4761233-A Novel membranes and process for making them MEMBRANE PRODUCTS KIRYAT WEIZMANN LTD. (IL) 1988-08-02 US disclosed
US-4720345-A Semipermeable membranes of modified styrene-based polymers, process for their manufacture and their use ALIGENA AG (CH) 1988-01-19 US disclosed
EP-0242761-A2 Composite membranes useful in the separation of low molecular weight organic compounds from aqueous solutions containing inorganic salts ALIGENA AG (CH) 1987-10-28 EP disclosed
US-4659474-A CROSSLINKING THIN POLYMER LAYER DEPOSITED ON POROUS SUBSTRATE ALIGENA AG (CH) 1987-04-21 US disclosed