SCHEMBL617385

SCHEMBL617385

C1=CC([Zr+2]2(C3C=Cc4ccccc43)CC2)c2ccccc21.Cc1ccc(S(=O)(=O)[O-])cc1.Cc1ccc(S(=O)(=O)[O-])cc1

nearest known ligand 0.35

Known targets — ChEMBL curated mechanism

CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.35
LMNA P02545 3/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPK1 P28482 1/20 0.34
THPO P40225 1/20 0.34
OXTR P30559 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
TERT O14746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GAA P10253 2/20 0.33
ACHE P22303 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
C5AR1 P21730 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3123699 0.88 ALDH1A1 (0.33) LMNACYP3A4MAPK1CA1CA2
SCHEMBL616673 0.87 BRD4 (0.33)
SCHEMBL6357318 0.82 HTR2A (0.33) LMNACYP3A4CYP2D6THPO
Hydrochloric Acid SCHEMBL8017987 0.81 HTR6 (0.33) LMNACYP3A4CYP2D6THPO
Trifluoromethanesulfonic Acid SCHEMBL619015 0.81 GPR3 (0.36) CYP2D6
Bromide SCHEMBL616105 0.79 HTR2A (0.39) LMNACYP3A4CYP2D6THPO
Hydrochloric Acid SCHEMBL648408 0.79 HTR2A (0.35) CYP2D6
Fluoride Ion SCHEMBL1130929 0.79 HTR2A (0.35) CYP2D6
SCHEMBL5839790 0.79 HTR2A (0.35) CYP2D6
Hydrochloric Acid SCHEMBL151866 0.79 HTR2A (0.35) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1632532-B1 SOLVENT DISPERSION OF COMPOSITE RESIN AND USES THEREOF MITSUI CHEMICALS INC (JP) 2018-12-05 EP disclosed
US-10087262-B2 Ethylene polymer, stretch-molded product obtained by stretching the same, and method for producing ethylene polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-10-02 US disclosed
US-20170298156-A1 ETHYLENE POLYMER, STRETCH-MOLDED PRODUCT OBTAINED BY STRETCHING THE SAME, AND METHOD FOR PRODUCING ETHYLENE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-10-19 US disclosed
EP-2423236-B1 METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2013-09-04 EP disclosed
US-8507603-B2 Solvent dispersion of composite resin and uses thereof MITSUI CHEMICALS, INC. (JP) 2013-08-13 US disclosed
US-8445609-B2 Method for producing olefin polymer MITSUI CHEMICALS, INC. (JP) 2013-05-21 US disclosed
EP-2423236-A1 METHOD FOR PRODUCING OLEFIN POLYMER Mitsui Chemicals, Inc. (JP) 2012-02-29 EP disclosed
US-20120041162-A1 METHOD FOR PRODUCING OLEFIN POLYMER PRIME POLYMER CO., LTD. 2012-02-16 US disclosed
US-20110054118-A1 Solvent dispersion of composite resin and uses thereof MITSUI CHEMICALS, INC. (JP) 2011-03-03 US disclosed
US-7879950-B2 Solvent dispersion of composite resin and uses thereof MITSUI CHEMICALS, INC. (JP) 2011-02-01 US disclosed
US-5292845-A Ethylene/alpha-olefin/7-methyl-1,6-octadiene copolymer rubber and composition of the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
EP-0582480-A2 Olefin polymerization catalyst and method for the polymerization of olefin using said polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-02-09 EP disclosed
EP-0575123-A2 Ethylene copolymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-12-22 EP disclosed
US-5252529-A Coordination catalyst using a moisture-adsorbed carrier of a metal oxide; addition polymers having excellent melt tension and moldability and broad molecular weight distribution MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-12 US disclosed
EP-0552946-A1 Ethylene/alpha-olefin/7-methyl-1,6-octadiene copolymer rubber and composition of the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP disclosed
EP-0552945-A2 Process for the preparation of polyolefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP disclosed
EP-0536503-A2 Olefin polymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-14 EP disclosed
EP-0534119-A2 Prepolymerized olefin polymerization catalyst and olefin polymerization process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-03-31 EP disclosed
EP-0516458-A2 Olefin polymerization solid catalyst, olefin polymerization catalyst and olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-12-02 EP disclosed
EP-0515132-A2 Olefin polymerization catalyst and olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-11-25 EP disclosed