Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174201 | 0.93 | MAOB (0.57) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL27352953 | 0.90 | MAOB (0.54) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL2152475 | 0.74 | MAOB (0.73) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL68983 | 0.74 | MAOB (1.00) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL339009 | 0.74 | NR4A2 (1.00) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL7908051 | 0.74 | SRD5A2 (0.85) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL30207018 | 0.74 | NR4A2 (1.00) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| Hydrochloric Acid SCHEMBL4748074 | 0.72 | NR4A2 (0.97) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL3442746 | 0.72 | NR4A2 (0.79) | MAOBNR4A2SMPD1SRD5A2PTPN1 | |
| SCHEMBL2498876 | 0.72 | MAOB (0.64) | MAOBNR4A2SMPD1SRD5A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203770-B1 | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hyperplasia and other diseases | UPJOHN CO (US) | 2005-03-09 | — | — | EP | disclosed |
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1203770-A1 | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hyperplasia and other diseases | PHARMACIA & UPJOHN COMPANY (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-1994011361-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-05-26 | — | — | WO | disclosed |