Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174842 | 0.89 | PGR (0.41) | PGRHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10414302 | 0.83 | PPOX (0.46) | PPOXBRD4 | |
| SCHEMBL6921397 | 0.83 | PPOX (0.34) | PPOXBRD4 | |
| SCHEMBL6106477 | 0.82 | DHODH (0.40) | PGRPPOX | |
| SCHEMBL6316627 | 0.81 | PPOX (0.40) | PGRPPOX | |
| SCHEMBL7627173 | 0.77 | PGR (0.35) | PGRPPOXBRD4 | |
| SCHEMBL6174881 | 0.77 | HTR1A (0.34) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8323113 | 0.74 | PGR (0.35) | PGR | |
| SCHEMBL7686693 | 0.74 | PPOX (0.62) | PPOX | |
| SCHEMBL8829573 | 0.74 | PPOX (0.35) | PPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189893-B1 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONE | BAYER CROPSCIENCE AG (DE) | 2005-09-07 | — | — | EP | disclosed |
| US-6608004-B2 | Nitrogen compounds such as 2-(5-(N-phenoxy-carbonyl-N-ethyl-sulphonylamino)-4-cyano-2-fluoro-phenyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione, used as postemergence herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-19 | — | — | US | disclosed |
| US-20030069140-A1 | Substitutes 2-aryl-1,2,4-triazine-3,5-di(thi)one | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069140-A1 | Substitutes 2-aryl-1,2,4-triazine-3,5-di(thi)one | DDT, SULT1E1, CYP1A1 | PGR 3988/4885HTR1A 276/4885ADRA1D 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.