SCHEMBL8323113

SCHEMBL8323113

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(NS(C)(=O)=O)c(C#N)cc2F)c1=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.35
BCAT2 O15382 7/20 0.35
BCAT1 P54687 7/20 0.35
KIF11 P52732 2/20 0.31
NR3C1 P04150 1/20 0.31
NR3C2 P08235 1/20 0.31
AR P10275 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8853791 0.92 BCAT2 (0.35) PGRBCAT2BCAT1KIF11
SCHEMBL7212890 0.90 PGR (0.39) PGRBCAT2BCAT1AR
SCHEMBL8853375 0.89 JAK2 (0.33) BCAT2BCAT1AR
SCHEMBL8466083 0.89 BCAT2 (0.34) PGRBCAT2BCAT1
SCHEMBL8925239 0.89 BCAT2 (0.35) PGRBCAT2BCAT1KIF11NR3C1
SCHEMBL7627173 0.86 PGR (0.35) PGRBCAT2BCAT1NR3C1NR3C2
SCHEMBL5361878 0.84 PPOX (0.40) KIF11ALDH1A1
SCHEMBL8193759 0.83 BCAT2 (0.40) BCAT2BCAT1AR
SCHEMBL7653459 0.82 BCAT2 (0.35) BCAT2BCAT1AR
SCHEMBL8465633 0.82 AR (0.37) PGRBCAT2BCAT1ARALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990044-A Selective herbicides based on aryl uracils BAYER AKTIENGESELLSCHAFT (DE) 1999-11-23 US disclosed
US-5900483-A Process for the separation of phenyluracil compounds NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-05-04 US disclosed
US-5641725-A Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US disclosed
EP-0714602-A1 Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1996-06-05 EP disclosed