Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 5/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | CBLB | Q13191 | 3/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GIPR | P48546 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175302 | 0.92 | GRM5 (0.45) | LIPECBLBSLC5A1ABL1 | |
| SCHEMBL6177007 | 0.88 | TDP1 (0.42) | LIPECBLBSLC5A1PDE2A | |
| SCHEMBL6175275 | 0.87 | IGF1R (0.41) | NPC1RAB9ACBLBTRPV1 | |
| SCHEMBL6172184 | 0.86 | NPC1 (0.39) | NPC1RAB9ACBLBMEN1KMT2A | |
| SCHEMBL6173626 | 0.86 | SLC5A1 (0.37) | CBLBSLC5A1ABL1PDE2A | |
| SCHEMBL6177220 | 0.85 | LMNA (0.40) | LIPESLC5A1TRPV1PDE2A | |
| SCHEMBL6172737 | 0.85 | MAPK1 (0.37) | CBLBSLC5A1PDE2A | |
| SCHEMBL6172084 | 0.84 | LMNA (0.40) | SLC5A1PDE2A | |
| SCHEMBL6177704 | 0.84 | KDR (0.42) | SLC5A1 | |
| SCHEMBL6171770 | 0.84 | LMNA (0.43) | CBLBSLC5A1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |