Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173783 | 0.94 | LMNA (0.44) | NPC1RAB9AKMT2ALMNAGAA | |
| SCHEMBL6175145 | 0.93 | ALDH1A1 (0.40) | NPC1RAB9AKMT2ATSHRLMNA | |
| SCHEMBL6753615 | 0.92 | GAA (0.46) | NPC1RAB9AKMT2ATP53LMNA | |
| SCHEMBL6175398 | 0.88 | GRM5 (0.43) | NPC1RAB9AKMT2ATSHRTP53 | |
| SCHEMBL6173230 | 0.86 | IGF1R (0.44) | NPC1RAB9AKMT2ATSHRHTR1F | |
| SCHEMBL6175553 | 0.86 | NPC1 (0.40) | NPC1RAB9AKMT2ATSHRHTR1F | |
| SCHEMBL6175127 | 0.85 | CYP2C9 (0.38) | NPC1RAB9ATP53LMNAGAA | |
| SCHEMBL6173058 | 0.85 | IGF1R (0.36) | KMT2ATSHRLMNAGAAALDH1A1 | |
| SCHEMBL6175073 | 0.85 | IGF1R (0.38) | RAB9AKMT2ATSHRTP53LMNA | |
| SCHEMBL6175269 | 0.84 | MAPT (0.40) | KMT2AGAAALDH1A1ARCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |