SCHEMBL617443

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14537089	0.87	GAA (0.47)	MAPTMEN1ALDH1A1LMNAPOLB
	SCHEMBL619248	0.76	FYN (0.52)	MAPTMEN1ALDH1A1GAAHPGD
	SCHEMBL10189278	0.70	UGT1A1 (0.41)	ESR1ESR2MAPTKDM4EMEN1
	SCHEMBL1167769	0.70	HSP90AA1 (0.56)	ESR1ESR2ALOX5USP7MAPT
	SCHEMBL619216	0.68	TUBB4A (0.58)	CDK2
	SCHEMBL617854	0.67	PTGS2 (0.50)	ESR1ESR2ALOX5USP7RPS6KA3
	SCHEMBL1168336	0.64	RPS6KA3 (0.43)	ESR1ESR2ALOX5USP7MEN1
	SCHEMBL17625725	0.64	BACE1 (0.60)	ESR1ESR2ALOX5USP7MAPT
	SCHEMBL411503	0.63	RPS6KA3 (0.39)	ESR1ALOX5MAPTMEN1USP2
	SCHEMBL17625678	0.63	ALOX5 (0.68)	ESR1ESR2ALOX5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.