Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 16/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175093 | 0.90 | IGF1R (0.44) | IGF1RPDE2A | |
| SCHEMBL6177171 | 0.90 | IGF1R (0.46) | IGF1RPDE2A | |
| SCHEMBL6175310 | 0.89 | MCHR1 (0.35) | MCHR1PDE2A | |
| SCHEMBL6174416 | 0.88 | IGF1R (0.33) | IGF1R | |
| SCHEMBL6177806 | 0.83 | IGF1R (0.43) | IGF1RPDE2A | |
| SCHEMBL6172178 | 0.83 | IGF1R (0.33) | IGF1RMCHR1 | |
| SCHEMBL6174760 | 0.80 | IGF1R (0.41) | IGF1RPDE2A | |
| SCHEMBL6174018 | 0.80 | SLC5A1 (0.36) | IGF1RPDE2A | |
| SCHEMBL6176013 | 0.80 | IGF1R (0.41) | IGF1RPDE2A | |
| SCHEMBL6175275 | 0.80 | IGF1R (0.41) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |