Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | KMO | O15229 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 9/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230486 | 0.88 | HTR7 (0.59) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL4515283 | 0.83 | KDM4E (0.58) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL4515279 | 0.83 | KDM4E (0.58) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL32688379 | 0.82 | ALDH1A1 (0.80) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL5863335 | 0.82 | KDM4E (0.57) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL63379 | 0.81 | KDM4E (0.54) | KDM4EMEN1KMT2AENPP2DRD2 | |
| SCHEMBL29631156 | 0.81 | ALDH1A1 (0.73) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL3319386 | 0.81 | ALDH1A1 (0.73) | KDM4EMEN1ALDH1A1GAAHPGD | |
| SCHEMBL6420684 | 0.81 | ALOX5 (0.52) | MEN1ALDH1A1KMT2ADRD2HTR7 | |
| SCHEMBL4021071 | 0.81 | DRD2 (0.68) | KDM4EMEN1ALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530564-A2 | COMPOUNDS DERIVED FROM ARYL CARBAMATES, PREPARATION THEREOF AND USES OF SAME | Cerep (FR) | 2005-05-18 | — | — | EP | disclosed |
| WO-2004018436-A2 | COMPOUNDS DERIVED FROM ARYL CARBAMATES, PREPARATION THEREOF AND USES OF SAME | CEREP (FR) | 2004-03-04 | — | — | WO | disclosed |