Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.58 |
| ▸ | DRD4 | P21917 | 8/20 | 0.55 |
| ▸ | DRD2 | P14416 | 7/20 | 0.55 |
| ▸ | DRD3 | P35462 | 7/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15265729 | 0.82 | HTR1A (0.55) | HTR1AMTNR1ADRD4DRD2DRD3 | |
| SCHEMBL8113788 | 0.82 | HTR1A (0.57) | HTR1AMTNR1ASLC6A4KDM4E | |
| SCHEMBL15264912 | 0.82 | HTR1A (0.60) | HTR1AMTNR1ADRD2SLC6A4KDM4E | |
| Hydrochloric Acid SCHEMBL9281629 | 0.81 | HTR1A (0.56) | HTR1AMTNR1ASLC6A4KDM4E | |
| SCHEMBL6174714 | 0.81 | MTNR1A (0.71) | HTR1AMTNR1ADRD2SLC6A4 | |
| SCHEMBL15266096 | 0.80 | HTR1A (0.56) | HTR1AMTNR1ADRD4DRD2DRD3 | |
| SCHEMBL15266097 | 0.80 | HTR1A (0.52) | HTR1AMTNR1ADRD4DRD2DRD3 | |
| SCHEMBL7518458 | 0.79 | MTNR1A (0.69) | HTR1AMTNR1ADRD2SLC6A4KDM4E | |
| SCHEMBL5926589 | 0.79 | MTNR1A (0.69) | HTR1AMTNR1ADRD2SLC6A4 | |
| SCHEMBL11701339 | 0.78 | DRD4 (0.77) | HTR1ADRD4DRD2DRD3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930110-B2 | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same | EGIS GYOGYSZERGYAR RT. (HU) | 2005-08-16 | — | — | US | disclosed |
| EP-1430047-B1 | SUBSTITUTED ALKYLAMINOPYRIDAZINONE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2005-02-09 | — | — | EP | disclosed |
| US-20040242873-A1 | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same | EGIS GYOGYSZERGYAR RT. (HU) | 2004-12-02 | — | — | US | disclosed |
| EP-1430047-A1 | SUBSTITUTED ALKYLAMINOPYRIDAZINONE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Egis Gyogyszergyar Rt. (HU) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003027097-A1 | SUBSTITUTED ALKYLAMINOPYRIDAZINONE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | EGIS Gyógyszergyár Rt. (HU) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242873-A1 | Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same | CYP3A5, CYP11B1, ADRA1D | HTR1A 39/4885MTNR1A 603/4885DRD4 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.