Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | MARS1 | P56192 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172398 | 0.92 | MAT2A (0.43) | MAT2AMAPTSCN10AL3MBTL1POLB | |
| SCHEMBL6176736 | 0.92 | MAT2A (0.38) | MAT2AMAPTSCN10AL3MBTL1POLB | |
| SCHEMBL6173212 | 0.87 | ADRB3 (0.40) | MAPTL3MBTL1POLBNPBWR1MCHR1 | |
| SCHEMBL6173751 | 0.86 | NPBWR1 (0.35) | MAPTL3MBTL1POLBNPBWR1MCHR1 | |
| SCHEMBL6175911 | 0.85 | THRB (0.38) | MAPTPTGS1PTGS2ARCYP2C9 | |
| SCHEMBL6174008 | 0.84 | POLB (0.41) | MAPTL3MBTL1POLBMAPK1NPBWR1 | |
| SCHEMBL17558396 | 0.84 | POLB (0.39) | L3MBTL1POLBMAPK1NPBWR1MCHR1 | |
| SCHEMBL6175359 | 0.83 | POLB (0.38) | L3MBTL1POLBMAPK1NPBWR1MCHR1 | |
| SCHEMBL6171486 | 0.81 | POLB (0.39) | L3MBTL1POLBNPBWR1MCHR1SCN9A | |
| SCHEMBL6171179 | 0.81 | POLB (0.37) | L3MBTL1POLBMAPK1NPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |