Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177182 | 0.90 | ALDH1A1 (0.36) | CYP3A4GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6173183 | 0.89 | CYP3A4 (0.39) | CYP3A4GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6173098 | 0.89 | FLT1 (0.36) | CYP3A4GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6207150 | 0.87 | CCR9 (0.44) | CYP3A4GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6174555 | 0.87 | IGF1R (0.40) | CYP3A4GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6172456 | 0.86 | IGF1R (0.42) | AR | |
| SCHEMBL6224943 | 0.86 | CCR9 (0.46) | CYP2C9CCR9MAPTNAMPTKMT2A | |
| SCHEMBL6173837 | 0.86 | LIPE (0.38) | CYP3A4GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6173294 | 0.86 | CYP3A4 (0.38) | CYP3A4GAACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6172191 | 0.85 | AOC1 (0.38) | CYP3A4GAACYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |