Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GALR2 | O43603 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6172238 | 0.87 | KDM4E (0.39) | KDM4EL3MBTL1GAAACHEALDH1A1 | |
| SCHEMBL6174312 | 0.85 | POLB (0.40) | L3MBTL1POLBMGLLACP1 | |
| SCHEMBL6173653 | 0.85 | BACE1 (0.38) | L3MBTL1POLBMGLLPDE2AACP1 | |
| SCHEMBL6175476 | 0.85 | IGF1R (0.43) | MCHR1KDM4EL3MBTL1POLBMGLL | |
| SCHEMBL6172147 | 0.84 | POLB (0.37) | L3MBTL1GAAALDH1A1POLBMGLL | |
| SCHEMBL6175741 | 0.84 | POLB (0.37) | L3MBTL1POLBMGLLLMNAPDE2A | |
| SCHEMBL6175470 | 0.83 | ACP1 (0.41) | L3MBTL1POLBMGLLPDE2AACP1 | |
| SCHEMBL6173635 | 0.81 | CCR6 (0.35) | MCHR1KDM4EL3MBTL1POLBMAPT | |
| SCHEMBL6175751 | 0.80 | AR (0.41) | L3MBTL1GAAALDH1A1POLB | |
| SCHEMBL6173665 | 0.78 | MAPT (0.36) | KDM4EL3MBTL1GAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |