Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4611963 | 0.98 | HSD11B1 (0.37) | HSD11B1HSD11B2CYP1A2KDM4EKMT2A | |
| Formic Acid SCHEMBL4941735 | 0.94 | HSD11B1 (0.35) | HSD11B1HSD11B2CYP1A2KDM4EKMT2A | |
| SCHEMBL6508506 | 0.79 | CYP1A2 (0.37) | HSD11B1CYP1A2KDM4EKMT2ACA2 | |
| SCHEMBL7994140 | 0.77 | CA2 (0.39) | HSD11B1HSD11B2CYP1A2KDM4ECA2 | |
| SCHEMBL1127702 | 0.77 | ALDH1A1 (0.49) | KDM4ESMN1; SMN2GAALMNACYP2C19 | |
| SCHEMBL6543859 | 0.77 | ALDH1A1 (0.49) | KDM4ESMN1; SMN2GAALMNACYP2C19 | |
| SCHEMBL6160228 | 0.76 | CYP1A2 (0.33) | CYP1A2KDM4EKMT2AALDH1A1 | |
| SCHEMBL6512207 | 0.76 | CYP1A2 (0.41) | CYP1A2KDM4EKMT2ACA2CHKA | |
| SCHEMBL3898636 | 0.76 | CA2 (0.36) | CYP1A2KDM4EKMT2ACA2CHKA | |
| SCHEMBL4610760 | 0.75 | CA2 (0.47) | HSD11B1CYP1A2KMT2ACA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1249059-C | novel piperidine carboxylic acid amide derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2006-04-05 | — | — | CN | disclosed |
| EP-1395582-B1 | NOVEL PIPERIDINECARBOXAMIDE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2005-05-04 | — | — | EP | disclosed |
| CN-1518549-A | Novel piperidinecarboxamide derivatives, method for preparing same and pharmaceutical compositions containing same | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-08-04 | — | — | CN | disclosed |
| EP-1395582-A1 | NOVEL PIPERIDINECARBOXAMIDE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094821-A1 | NOVEL PIPERIDINECARBOXAMIDE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-11-28 | — | — | WO | disclosed |