Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175645 | 0.94 | HSD11B1 (0.38) | HSD11B1HSD11B2CYP1A2KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL4611963 | 0.92 | HSD11B1 (0.37) | HSD11B1HSD11B2CYP1A2KDM4EKMT2A | |
| Formic Acid SCHEMBL3898988 | 0.80 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2 | |
| SCHEMBL4941740 | 0.76 | HSD11B1 (0.35) | HSD11B1HSD11B2CYP3A4SMN1; SMN2 | |
| SCHEMBL6508506 | 0.74 | CYP1A2 (0.37) | HSD11B1CYP1A2KDM4EKMT2ACA2 | |
| SCHEMBL6543859 | 0.72 | ALDH1A1 (0.49) | KDM4ESMN1; SMN2 | |
| SCHEMBL7994140 | 0.72 | CA2 (0.39) | HSD11B1HSD11B2CYP1A2KDM4ECA2 | |
| SCHEMBL1127702 | 0.72 | ALDH1A1 (0.49) | KDM4ESMN1; SMN2 | |
| SCHEMBL6160228 | 0.72 | CYP1A2 (0.33) | CYP1A2KDM4EKMT2A | |
| SCHEMBL6512207 | 0.71 | CYP1A2 (0.41) | CYP1A2KDM4EKMT2ACA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261976-A1 | NOVEL PIPERIDINECARBOXAMIDE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-AVENTIS (FR) | 2008-10-23 | — | — | US | disclosed |
| CN-1249059-C | novel piperidine carboxylic acid amide derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2006-04-05 | — | — | CN | disclosed |
| US-20040180890-A1 | Novel piperidinecarboxamide derivatives, method for preparing same and pharmaceutical compositions containing same | SANOFI-AVENTIS (FR) | 2004-09-16 | — | — | US | disclosed |
| CN-1518549-A | Novel piperidinecarboxamide derivatives, method for preparing same and pharmaceutical compositions containing same | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-08-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261976-A1 | NOVEL PIPERIDINECARBOXAMIDE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | TACR2, TACR1, KIT | HSD11B1 3987/4885HSD11B2 3012/4885CYP1A2 1586/4885 |
| US-20040180890-A1 | Novel piperidinecarboxamide derivatives, method for preparing same and pharmaceutical compositions containing same | KIT, TACR2, P2RX3 | HSD11B1 4116/4885HSD11B2 3397/4885CYP1A2 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.