Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205229 | 0.86 | PTGDR2 (0.37) | PPARGPPARDPPARAMRGPRX4PTGDR2 | |
| SCHEMBL5206113 | 0.83 | ADAMTS5 (0.48) | PPARGPPARDPPARAANO1MRGPRX4 | |
| SCHEMBL7834257 | 0.82 | MRGPRX4 (0.50) | PPARGPPARDPPARAANO1MRGPRX4 | |
| SCHEMBL25379733 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1HPGDHTT | |
| SCHEMBL5205234 | 0.76 | TSHR (0.46) | PPARGPPARDPPARAANO1MRGPRX4 | |
| SCHEMBL5350074 | 0.73 | PPARG (0.51) | PPARGPPARDPPARAANO1PTGDR2 | |
| SCHEMBL7834277 | 0.73 | FFAR1 (0.44) | PPARGFFAR1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL5201777 | 0.73 | P2RY1 (0.43) | PPARGPPARDPPARAANO1MRGPRX4 | |
| SCHEMBL5205774 | 0.73 | ADAMTS5 (0.40) | PPARGPPARDPPARAMRGPRX4PTGDR2 | |
| SCHEMBL5208318 | 0.72 | HDAC1 (0.43) | PTGDR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |