Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204934 | 0.90 | PTGES (0.39) | PTGESHDAC8MEN1KMT2AFFAR1 | |
| SCHEMBL5205144 | 0.90 | CACNA1B (0.44) | PTGDR2PTGESHDAC8MEN1KMT2A | |
| SCHEMBL5201777 | 0.89 | P2RY1 (0.43) | PTGDR2HDAC8MEN1KMT2AFFAR1 | |
| SCHEMBL5205229 | 0.87 | PTGDR2 (0.37) | PTGDR2PTGESHDAC8FFAR1MRGPRX4 | |
| SCHEMBL5206113 | 0.82 | ADAMTS5 (0.48) | ADAMTS5PTGDR2HDAC8FFAR1MRGPRX4 | |
| SCHEMBL5201809 | 0.82 | FFAR1 (0.49) | PTGESFFAR1ALOX5PPARGPPARD | |
| SCHEMBL5205589 | 0.81 | CACNA1B (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5208318 | 0.80 | HDAC1 (0.43) | ADAMTS5PTGDR2FFAR1 | |
| SCHEMBL6177750 | 0.80 | ADAMTS5 (0.44) | ADAMTS5PTGDR2FFAR1MRGPRX4ACLY | |
| SCHEMBL5206121 | 0.79 | MEN1 (0.41) | PTGDR2PTGESMEN1KMT2AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |