Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205774 | 0.87 | ADAMTS5 (0.40) | PTGDR2PPARGPPARDPPARAMRGPRX4 | |
| SCHEMBL6176779 | 0.86 | PPARG (0.46) | PTGDR2PPARGPPARDPPARAMRGPRX4 | |
| SCHEMBL5201777 | 0.85 | P2RY1 (0.43) | PTGDR2PPARGPPARDPPARAMRGPRX4 | |
| SCHEMBL5204934 | 0.78 | PTGES (0.39) | FFAR1PTGESHDAC8 | |
| SCHEMBL5205144 | 0.77 | CACNA1B (0.44) | PTGDR2FFAR1PTGESHDAC8 | |
| SCHEMBL5206121 | 0.76 | MEN1 (0.41) | PTGDR2PPARGPPARDPPARAMRGPRX4 | |
| SCHEMBL5204827 | 0.72 | TDP1 (0.41) | PTGES | |
| SCHEMBL5205589 | 0.70 | CACNA1B (0.50) | ALDH1A1 | |
| SCHEMBL5206113 | 0.69 | ADAMTS5 (0.48) | PTGDR2PPARGPPARDPPARAMRGPRX4 | |
| SCHEMBL5201809 | 0.69 | FFAR1 (0.49) | PPARGPPARDPPARAFFAR1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |