Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180534 | 0.79 | MEN1 (0.48) | MAPTGAAALDH1A1RAB9AKMT2A | |
| SCHEMBL6179386 | 0.79 | GAA (0.49) | MAPTGAAALDH1A1KDM4ERAB9A | |
| SCHEMBL6178909 | 0.79 | MAPT (0.45) | MAPTGAAALDH1A1KDM4ERAB9A | |
| SCHEMBL6179197 | 0.78 | LMNA (0.48) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6178784 | 0.78 | GAA (0.48) | MAPTGAAALDH1A1KDM4ERAB9A | |
| SCHEMBL6178841 | 0.73 | MAPK1 (0.51) | MAPTGAAALDH1A1RAB9AKMT2A | |
| SCHEMBL19861988 | 0.72 | ALDH1A1 (0.53) | MAPTGAAALDH1A1RAB9AKMT2A | |
| SCHEMBL26812628 | 0.71 | SMN1; SMN2 (0.70) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL4317620 | 0.71 | ALDH1A1 (0.57) | MAPTGAAALDH1A1KDM4ERAB9A | |
| SCHEMBL1922107 | 0.71 | MAPT (0.62) | MAPTGAAALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | claimed |