Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180534 | 0.88 | MEN1 (0.48) | MAPTMEN1KMT2APOLBTP53 | |
| SCHEMBL6179386 | 0.84 | GAA (0.49) | MAPTMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL6178784 | 0.83 | GAA (0.48) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6176850 | 0.79 | MAPT (0.50) | MAPTMEN1KMT2ATP53BLM | |
| SCHEMBL6178286 | 0.76 | MAPT (0.49) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6179197 | 0.74 | LMNA (0.48) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6181312 | 0.72 | MEN1 (0.48) | MAPTMEN1KMT2APOLBTP53 | |
| SCHEMBL6178509 | 0.72 | CA1 (0.46) | MAPTMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL15946681 | 0.70 | MAPK3 (0.53) | MAPK1 | |
| SCHEMBL19861988 | 0.69 | ALDH1A1 (0.53) | MAPTMEN1KMT2ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | claimed |