Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178909 | 0.88 | MAPT (0.45) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL6181312 | 0.84 | MEN1 (0.48) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL6179197 | 0.83 | LMNA (0.48) | MEN1KMT2AMAPTPOLBCA1 | |
| SCHEMBL6176850 | 0.79 | MAPT (0.50) | MEN1KMT2AMAPTTP53BLM | |
| SCHEMBL6179386 | 0.75 | GAA (0.49) | MEN1KMT2AMAPTBLMCA1 | |
| SCHEMBL6178784 | 0.74 | GAA (0.48) | MEN1KMT2AMAPTPOLBCA1 | |
| SCHEMBL6178286 | 0.73 | MAPT (0.49) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL19861988 | 0.69 | ALDH1A1 (0.53) | MEN1KMT2AMAPTTP53CA1 | |
| SCHEMBL26812628 | 0.68 | SMN1; SMN2 (0.70) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL4937983 | 0.66 | MAPT (0.61) | MEN1KMT2AMAPTTP53BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | disclosed |
| US-6872729-B2 | Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural fungicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6576631-B1 | Broad disease control spectrum; residual effectiveness, rainfastness; nondamaging to crops | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1132387-A1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | CBR3, TH, CASP3 | MEN1 1679/4885KMT2A 967/4885MAPT 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.