SCHEMBL617785

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL617990	0.91	TSHR (0.39)	TDP1POLQKITKMT2AMAPT
	SCHEMBL617531	0.85	KMT2A (0.41)	TDP1NPC1POLQKITKMT2A
	SCHEMBL616903	0.83	PTGS2 (0.40)	TDP1NPC1KITKMT2AMAPT
	SCHEMBL616535	0.83	PTGS2 (0.40)	TDP1NPC1KITKMT2AMAPT
	SCHEMBL616626	0.83	KIT (0.38)	TDP1KITKMT2AMAPTMEN1
	SCHEMBL615782	0.83	HSP90AA1 (0.44)	TDP1KITKMT2AMAPTMEN1
	SCHEMBL615930	0.82	TUBB4A (0.44)	KITMAPTALDH1A1KDM4EHPGD
	SCHEMBL1167540	0.82	TARBP2 (0.42)	TARBP2TDP1L3MBTL1NPC1KIT
	SCHEMBL617862	0.81	PTGS2 (0.40)	TDP1KITKMT2AMAPTMEN1
	SCHEMBL618939	0.81	TARBP2 (0.42)	TARBP2TDP1L3MBTL1NPC1KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.