Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178088 | 1.00 | ALDH1A1 (0.38) | ALDH1A1HTTHTR2CSLC6A2SLC6A4 | |
| SCHEMBL4439803 | 0.84 | HTR2C (0.35) | ALDH1A1HTTHTR2CSLC6A2SLC6A4 | |
| SCHEMBL27769842 | 0.81 | SLC6A2 (0.43) | ALDH1A1HTTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8290753 | 0.74 | L3MBTL1 (0.38) | SIGMAR1CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL31376861 | 0.74 | L3MBTL1 (0.38) | SIGMAR1CHRM2CHRM1CHRM3LMNA | |
| SCHEMBL29271953 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HTTMEN1LMNAKMT2A | |
| SCHEMBL29271950 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HTTMEN1LMNAKMT2A | |
| SCHEMBL1028438 | 0.70 | SLC6A2 (0.57) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL17884678 | 0.70 | SLC6A2 (0.57) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL17884836 | 0.70 | SLC6A2 (0.57) | HTR2CSLC6A2SLC6A4SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529043-A1 | NOVEL PROCESS | Biovitrum AB (SE) | 2005-05-11 | — | — | EP | claimed |
| WO-2004000829-A1 | NOVEL PROCESS | BIOVITRUM AB (SE) | 2003-12-31 | — | — | WO | claimed |