Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180773 | 0.86 | RAB9A (0.55) | RAB9AKCNMA1CA1CA2CA9 | |
| SCHEMBL6180141 | 0.84 | AKR1C3 (0.54) | RAB9AKCNMA1LMNAALDH1A1MAPK1 | |
| SCHEMBL6177283 | 0.83 | RAB9A (0.60) | RAB9ACA1CA2CA9GAA | |
| SCHEMBL6178609 | 0.78 | KCNMA1 (0.49) | RAB9AKAT2BKCNMA1LMNACYP3A4 | |
| SCHEMBL6178509 | 0.78 | CA1 (0.46) | RAB9ACA1CA2CA9CFTR | |
| SCHEMBL6178286 | 0.75 | MAPT (0.49) | KAT2BKCNMA1LMNACYP3A4TSHR | |
| SCHEMBL6178801 | 0.75 | MAPT (0.49) | RAB9AKAT2BKCNMA1LMNACYP3A4 | |
| SCHEMBL6250970 | 0.70 | KAT2B (0.66) | RAB9AKAT2BKCNMA1LMNACYP3A4 | |
| SCHEMBL17546158 | 0.70 | KAT2B (0.60) | RAB9AKAT2BKCNMA1LMNACYP3A4 | |
| SCHEMBL17486820 | 0.69 | MEN1 (0.69) | RAB9AKAT2BKCNMA1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | claimed |