Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178670 | 0.86 | ALDH1A1 (0.57) | MAPTKCNMA1KMT2AALDH1A1HTT | |
| SCHEMBL6178801 | 0.86 | MAPT (0.49) | MAPTKCNMA1LMNAKMT2AALDH1A1 | |
| SCHEMBL6178936 | 0.85 | L3MBTL1 (0.53) | MAPTKCNMA1LMNAKMT2AALDH1A1 | |
| SCHEMBL6178841 | 0.82 | MAPK1 (0.51) | MAPTKMT2AALDH1A1HTTMAPK1 | |
| SCHEMBL6178609 | 0.81 | KCNMA1 (0.49) | MAPTKCNMA1LMNAKMT2AALDH1A1 | |
| SCHEMBL6178909 | 0.76 | MAPT (0.45) | MAPTLMNAKMT2AALDH1A1HTT | |
| SCHEMBL6178417 | 0.75 | RAB9A (0.56) | MAPTKCNMA1LMNAKMT2AALDH1A1 | |
| SCHEMBL6180534 | 0.73 | MEN1 (0.48) | MAPTLMNAKMT2AALDH1A1HTT | |
| SCHEMBL17486820 | 0.72 | MEN1 (0.69) | MAPTKCNMA1LMNAKMT2AALDH1A1 | |
| SCHEMBL6176751 | 0.72 | GAA (0.59) | MAPTKCNMA1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | claimed |
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | disclosed |
| US-6872729-B2 | Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural fungicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6576631-B1 | Broad disease control spectrum; residual effectiveness, rainfastness; nondamaging to crops | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1132387-A1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | CBR3, TH, CASP3 | MAPT 4164/4885KCNMA1 1409/4885LMNA 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.