Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178230 | 0.85 | L3MBTL1 (0.60) | KCNMA1TSHRNFKB1ALDH1A1L3MBTL1 | |
| SCHEMBL6176751 | 0.82 | GAA (0.59) | KCNMA1CYP3A4ALDH1A1L3MBTL1MAPT | |
| SCHEMBL6178801 | 0.81 | MAPT (0.49) | KCNMA1TSHRCYP3A4KAT2BALDH1A1 | |
| SCHEMBL6178286 | 0.81 | MAPT (0.49) | KCNMA1TSHRCYP3A4KAT2BALDH1A1 | |
| SCHEMBL6180492 | 0.79 | TSHR (0.57) | TSHRNFKB1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL6178417 | 0.78 | RAB9A (0.56) | KCNMA1TSHRCYP3A4KAT2BALDH1A1 | |
| SCHEMBL8973681 | 0.77 | NPC1 (0.56) | TSHRNFKB1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL8974866 | 0.77 | TSHR (0.58) | TSHRCYP3A4NFKB1ALDH1A1MAPT | |
| SCHEMBL8758312 | 0.77 | L3MBTL1 (0.64) | KCNMA1TSHRCYP3A4KAT2BALDH1A1 | |
| SCHEMBL14940507 | 0.74 | NFKB1 (0.53) | TSHRNFKB1ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | claimed |
| US-3939158-A | N-(2,4-dihalo-S-triazin-6-yl)-ureas and process for their manufacture | CIBA-GEIGY AG (CH) | 1976-02-17 | — | — | US | disclosed |