Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178821 | 0.97 | RAB9A (0.49) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL6180795 | 0.92 | MAPT (0.47) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL6177999 | 0.85 | KCNQ3 (0.47) | RAB9AL3MBTL1NPC1GAAMAPT | |
| SCHEMBL6180304 | 0.83 | MAPT (0.46) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL6179205 | 0.80 | RAB9A (0.57) | RAB9AL3MBTL1NPC1TNFNOD1 | |
| SCHEMBL6182050 | 0.78 | KCNQ3 (0.45) | RAB9AL3MBTL1NPC1GAAMAPT | |
| SCHEMBL6176705 | 0.78 | CDK8 (0.45) | RAB9ANPC1MAPTSMN1; SMN2HTR2C | |
| SCHEMBL6178617 | 0.77 | KEAP1 (0.46) | RAB9AKDM4EALDH1A1HTR2C | |
| SCHEMBL6179531 | 0.77 | KCNQ3 (0.45) | RAB9AL3MBTL1NPC1GAAMAPT | |
| SCHEMBL6178473 | 0.76 | RAB9A (0.53) | RAB9AL3MBTL1NPC1TNFNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066261-B1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMA CO LTD (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-6511995-B1 | Inhibits collagen synthesis, which is useful for prophylaxis or treatment of fibrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |