Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 4/20 | 0.36 |
| ▸ | CCKAR | P32238 | 3/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176423 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CCKBRCCKAR | |
| SCHEMBL1394353 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CCKBRCCKAR | |
| Oxalic Acid SCHEMBL6825172 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CCKBRCCKAR | |
| Oxalic Acid SCHEMBL6825177 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CCKBRCCKAR | |
| SCHEMBL6179979 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ACCKBRCCKAR | |
| SCHEMBL7962937 | 0.79 | MEN1 (0.41) | ALDH1A1SCN9AMEN1KMT2AAADAT | |
| SCHEMBL6180501 | 0.77 | CCKBR (0.44) | ALDH1A1CCKBRCCKAR | |
| SCHEMBL6177308 | 0.77 | PARP1 (0.40) | ALDH1A1SCN9ACCKBR | |
| SCHEMBL6193195 | 0.76 | CCKBR (0.46) | ALDH1A1CCKBRCCKAR | |
| SCHEMBL1394355 | 0.76 | CCKBR (0.46) | ALDH1A1CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |