Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179356 | 0.85 | GRM2 (0.35) | MEN1KMT2AGRM2AADATALDH1A1 | |
| Hydrochloric Acid SCHEMBL6177549 | 0.84 | GRM2 (0.34) | MEN1KMT2AGRM2AADATALDH1A1 | |
| SCHEMBL6180323 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AGRM2AADATALDH1A1 | |
| SCHEMBL6176328 | 0.75 | MEN1 (0.47) | MEN1KMT2AGRM2ALDH1A1SCN9A | |
| SCHEMBL7962381 | 0.73 | KYAT1 (0.40) | GRM2AADATALDH1A1GAATSHR | |
| SCHEMBL6178758 | 0.71 | KMT2A (0.42) | MEN1KMT2AGRM2SCN9AOPRM1 | |
| SCHEMBL6178763 | 0.71 | KMT2A (0.42) | MEN1KMT2AGRM2SCN9AOPRM1 | |
| SCHEMBL6176690 | 0.67 | KCNH2 (0.34) | MEN1KMT2AGRM2AADATSCN9A | |
| SCHEMBL7961430 | 0.67 | MTNR1A (0.40) | MEN1KMT2AGRM2ALDH1A1GAA | |
| SCHEMBL28779734 | 0.65 | PARK7 (0.42) | MEN1KMT2AAADATALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |