Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178038 | 0.87 | MAPK1 (0.44) | MAPK1PIK3CBACSS2RXRACACNA1D | |
| SCHEMBL6179656 | 0.83 | PIK3CD (0.47) | MAPK1PIK3CBPIK3CAPIK3CDALDH1A1 | |
| SCHEMBL6179131 | 0.80 | TLR8 (0.44) | RXRACACNA1DPIK3CAPIK3CDALDH1A1 | |
| SCHEMBL6181550 | 0.80 | PIK3CD (0.36) | ACSS2PIK3CAPIK3CDHTTMEN1 | |
| SCHEMBL15000806 | 0.73 | ALDH1A1 (0.46) | MAPK1ACSS2RXRAALDH1A1TSHR | |
| SCHEMBL175716 | 0.70 | KMT2A (0.47) | PIK3CAPIK3CDALDH1A1MEN1KMT2A | |
| SCHEMBL29361651 | 0.70 | KMT2A (0.47) | PIK3CAPIK3CDALDH1A1MEN1KMT2A | |
| SCHEMBL27527658 | 0.69 | PIK3CD (0.45) | PIK3CBPIK3CAPIK3CDALDH1A1HTT | |
| SCHEMBL12796754 | 0.69 | KMT2A (0.53) | PIK3CBACSS2PIK3CAALDH1A1APEX1 | |
| SCHEMBL13052930 | 0.68 | PIK3CD (0.48) | MAPK1PIK3CBPIK3CAPIK3CDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | disclosed |
| US-6872729-B2 | Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural fungicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6576631-B1 | Broad disease control spectrum; residual effectiveness, rainfastness; nondamaging to crops | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1132387-A1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | CBR3, TH, CASP3 | MAPK1 3221/4885PIK3CB 965/4885ACSS2 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.