Sugi Predict

Sugi Predict / Compounds / SCHEMBL175716

SCHEMBL175716

SCHEMBL175716

COc1cc(OC)nc(-n2c(C)nc3cc(Cl)ccc32)n1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.47
▸ PIK3CD O00329 1/20 0.45
▸ PIK3CA P42336 1/20 0.45
▸ PDE2A O00408 1/20 0.39
▸ PDE10A Q9Y233 1/20 0.39
▸ MAP3K14 Q99558 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ FABP4 P15090 1/20 0.38
▸ MAT2A P31153 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ MCHR1 Q99705 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ HSP90AA1 P07900 1/20 0.38
▸ HSP90AB1 P08238 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361651 1.00 KMT2A (0.47) KMT2APIK3CDPIK3CAPDE2APDE10A
SCHEMBL28897062 0.88 MAT2A (0.52) KMT2APIK3CDPIK3CAPDE2APDE10A
SCHEMBL13052931 0.86 KMT2A (0.55) KMT2APIK3CDPIK3CAPDE2AMAP3K14
SCHEMBL6180354 0.85 KMT2A (0.47) KMT2APIK3CDPIK3CAPDE2APDE10A
SCHEMBL6179656 0.85 PIK3CD (0.47) PIK3CDPIK3CATHRBTDP1ALDH1A1
SCHEMBL374122 0.80 HTT (0.56) PIK3CDPIK3CAALDH1A1RAB9A
SCHEMBL31026758 0.80 HTT (0.56) PIK3CDPIK3CAALDH1A1RAB9A
SCHEMBL20764769 0.79 AKR1C3 (0.39) KMT2ATDP1ALDH1A1MAT2AHPGD
SCHEMBL6181550 0.78 PIK3CD (0.36) KMT2APIK3CDPIK3CAPDE10ATHRB
SCHEMBL17276731 0.74 NR1H2 (0.47) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1932 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 — — EP claimed
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-11-06 — — US claimed
WO-2025223904-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-30 — — WO claimed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 — — EP claimed
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 — — US claimed
EP-4346412-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI Industries Ltd. (IN) 2024-04-10 — — EP claimed
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 — — CN claimed
US-20230397607-A1 COMPOSITIONS COMPRISING MEFENTRIFLUCONAZOLE BASF Agro B.V. (NL) 2023-12-14 — — US claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
CN-116209355-A Composition containing haloxyfop-methyl 巴斯夫农业公司 2023-06-02 — — CN claimed
WO-2010139653-A1 FUNGICIDAL MIXTURES COMPRISING HETERAROMATIC SULFONAMIDES BASF SE (DE) 2010-12-09 — — WO claimed
WO-2010128003-A2 A METHOD FOR INCREASING THE VIGOR AND/OR CROP YIELD OF AGRICULTURAL PLANTS UNDER ESSENTIALLY NON-EXISTENT PATHOGEN PRESSURE BASF SE (DE) 2010-11-11 — — WO claimed
WO-2010115720-A2 METHOD FOR COMBATING HARMFUL FUNGI BASF SE (DE) 2010-10-14 — — WO claimed
WO-2010103065-A1 FUNGICIDAL COMPOSITIONS AND THEIR USE BASF SE (DE) 2010-09-16 — — WO claimed
WO-2010072634-A2 POST-HARVEST TREATMENT METHOD BASF SE (DE) 2010-07-01 — — WO claimed
WO-2010069763-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2010-06-24 — — WO claimed
WO-2009147205-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2009-12-10 — — WO claimed
WO-2009071389-A1 FUNGICIDE MIXTURES BASF SE (DE) 2009-06-11 — — WO claimed
WO-2009071419-A1 FUNGICIDAL MIXTURES BASF SE (DE) 2009-06-11 — — WO claimed
WO-2009071450-A1 FUNGICIDAL MIXTURE BASF SE (DE) 2009-06-11 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH KMT2A 2611/4885PIK3CD 618/4885PIK3CA 681/4885
US-20230397607-A1 COMPOSITIONS COMPRISING MEFENTRIFLUCONAZOLE CYP51A1, CYP3A43, CYP3A7 KMT2A 2496/4885PIK3CD 249/4885PIK3CA 140/4885
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, ERG28 KMT2A 2692/4885PIK3CD 716/4885PIK3CA 774/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 KMT2A 3280/4885PIK3CD 608/4885PIK3CA 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.