Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181461 | 0.91 | CHRM4 (0.64) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL6178167 | 0.90 | ADORA2A (0.62) | KMT2AMEN1MAPTDUSP3ADORA2A | |
| SCHEMBL6177019 | 0.88 | MEN1 (0.54) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL14337671 | 0.86 | ALDH1A1 (0.57) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL6179672 | 0.86 | ALDH1A1 (0.57) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL6179726 | 0.86 | CHRM4 (0.52) | KMT2AMEN1MAPTALDH1A1TSHR | |
| SCHEMBL6180413 | 0.85 | ADORA2A (0.54) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL6180215 | 0.85 | ADORA2A (0.54) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL20702466 | 0.84 | ADORA1 (0.45) | KMT2AMEN1MAPTALDH1A1CHRM4 | |
| SCHEMBL29939645 | 0.84 | ADORA1 (0.45) | KMT2AMEN1MAPTALDH1A1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456202-B1 | BENZOTHIAZOLES | HOFFMANN LA ROCHE (CH) | 2005-11-09 | — | — | EP | disclosed |