Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178314 | 0.86 | KMT2A (0.40) | BACE1NUDT1KMT2AMAT2AALDH1A1 | |
| SCHEMBL6180354 | 0.86 | KMT2A (0.47) | KMT2AMAT2AALDH1A1PDE2APDE10A | |
| SCHEMBL29361651 | 0.71 | KMT2A (0.47) | KMT2AMAT2AALDH1A1PDE2APDE10A | |
| SCHEMBL175716 | 0.71 | KMT2A (0.47) | KMT2AMAT2AALDH1A1PDE2APDE10A | |
| SCHEMBL1977970 | 0.71 | BACE1 (0.56) | BACE1NUDT1KMT2AALDH1A1 | |
| SCHEMBL13052931 | 0.71 | KMT2A (0.55) | KMT2AALDH1A1POLBPDE2AMAP3K14 | |
| SCHEMBL6179131 | 0.70 | TLR8 (0.44) | ATRKMT2ACACNA1DALDH1A1POLB | |
| SCHEMBL2946987 | 0.69 | NOS2 (0.55) | BACE1NUDT1KMT2A | |
| SCHEMBL15595340 | 0.68 | BACE1 (0.64) | BACE1NUDT1KMT2AALDH1A1POLB | |
| SCHEMBL28897062 | 0.67 | MAT2A (0.52) | KMT2AMAT2APDE2APDE10AMAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132387-B1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | EP | disclosed |
| US-6872729-B2 | Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural fungicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6576631-B1 | Broad disease control spectrum; residual effectiveness, rainfastness; nondamaging to crops | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1132387-A1 | PYRIMIDINYLBENZIMIDAZOLE AND TRIAZINYLBENZIMIDAZOLE DERIVATIVES AND AGRICULTURA/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023966-A1 | Agricultural/ horticultural fungicides containing said derivatives as the active ingredients. | CBR3, TH, CASP3 | BACE1 2059/4885NUDT1 2198/4885ATR 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.