Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6178436 | 1.00 | L3MBTL1 (0.42) | L3MBTL1POLBALDH1A1HPGDKMT2A | |
| SCHEMBL6178442 | 1.00 | L3MBTL1 (0.42) | L3MBTL1POLBALDH1A1HPGDKMT2A | |
| SCHEMBL3631886 | 0.88 | KMT2A (0.53) | L3MBTL1POLBHPGDKMT2ATSHR | |
| SCHEMBL6178103 | 0.82 | ALDH1A1 (0.47) | L3MBTL1POLBALDH1A1HPGDTSHR | |
| SCHEMBL6178308 | 0.81 | HPGD (0.43) | HPGDKMT2ABRAFABCB1MAPT | |
| SCHEMBL6181372 | 0.81 | HPGD (0.43) | HPGDKMT2ABRAFABCB1MAPT | |
| SCHEMBL6178316 | 0.81 | HPGD (0.43) | HPGDKMT2ABRAFABCB1MAPT | |
| SCHEMBL6181402 | 0.81 | MAPT (0.49) | L3MBTL1POLBKMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL6179205 | 0.80 | RAB9A (0.57) | L3MBTL1ALDH1A1SMN1; SMN2MAPK1GAA | |
| SCHEMBL6178473 | 0.78 | RAB9A (0.53) | L3MBTL1MAPK1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066261-B1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMA CO LTD (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-6511995-B1 | Inhibits collagen synthesis, which is useful for prophylaxis or treatment of fibrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |