Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 8/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187774 | 0.96 | ABCB1 (0.58) | ABCB1ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL6185121 | 0.88 | ABCB1 (0.49) | ABCB1DRD2DRD1DRD5DRD3 | |
| SCHEMBL6185937 | 0.87 | DRD1 (0.51) | ABCB1DRD1DRD5KCNH2KDM4E | |
| SCHEMBL6185348 | 0.87 | ABCB1 (0.60) | ABCB1DRD2DRD1DRD5DRD3 | |
| SCHEMBL6185942 | 0.83 | ABCB1 (0.60) | ABCB1DRD2DRD1DRD5DRD3 | |
| SCHEMBL7236592 | 0.82 | DRD2 (0.53) | DRD2 | |
| SCHEMBL6185349 | 0.80 | ABCB1 (0.53) | ABCB1DRD2DRD1DRD5DRD3 | |
| SCHEMBL6186397 | 0.79 | HTR1D (0.42) | ABCB1KCNH2 | |
| SCHEMBL7235558 | 0.79 | HTR2A (0.49) | ADRA1ADRD2DRD1DRD3KCNH2 | |
| SCHEMBL6182420 | 0.79 | ABCB1 (0.50) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |