Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225838 | 0.96 | DRD2 (0.57) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL6185306 | 0.89 | HTR1A (0.48) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL6184834 | 0.85 | DRD2 (0.51) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL6185121 | 0.83 | ABCB1 (0.49) | DRD2 | |
| SCHEMBL6182349 | 0.82 | ABCB1 (0.58) | DRD2 | |
| SCHEMBL6185937 | 0.81 | DRD1 (0.51) | — | |
| SCHEMBL6182991 | 0.81 | HTR2A (0.53) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL6186397 | 0.80 | HTR1D (0.42) | HTR7 | |
| Hydrochloric Acid SCHEMBL7225841 | 0.80 | HTR2A (0.52) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL6187774 | 0.79 | ABCB1 (0.58) | DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |