SCHEMBL618379

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1168211	0.84	ALDH1A1 (0.40)	ALDH1A1KMT2AHTTKDM4EMEN1
	SCHEMBL616257	0.83	TUBB4A (0.41)	ALDH1A1KMT2AKDM4EHPGDCYP2C9
	SCHEMBL14847360	0.82	ALDH1A1 (0.42)	ALDH1A1KMT2AHTTKDM4EMEN1
	SCHEMBL615813	0.82	ALDH1A1 (0.42)	ALDH1A1KMT2AHTTKDM4EMEN1
	SCHEMBL617582	0.81	PTGS2 (0.40)	ALDH1A1KMT2AHTTKDM4EMEN1
	SCHEMBL617870	0.80	ALDH1A1 (0.41)	ALDH1A1KMT2AHTTKDM4EMEN1
	SCHEMBL410895	0.80	ALDH1A1 (0.46)	ALDH1A1KMT2AHTTKDM4EMEN1
	SCHEMBL617865	0.80	ALDH1A1 (0.42)	ALDH1A1KMT2AHTTKDM4EMEN1
	SCHEMBL1169106	0.80	KMT2A (0.39)	ALDH1A1KMT2AHTTKDM4EMEN1
	SCHEMBL618096	0.79	ALDH1A1 (0.40)	ALDH1A1KMT2AHTTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.